22 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... share the same pathophysiology ... overgrowth: • Carpal ... diagnosis #signs #symptoms ... endocrinology #pathophysiology
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Inadequate ADH SIADH - Excess ... Comparison #Table #Pathophysiology ... #Signs #Symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... lipid • GH excess ... expansion (e.g. carpal ... endocrinology #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Signs/Symptoms: ... endocrinology #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Accumulated micro-damage exceeds ... #orthopedics #pathophysiology ... #symptoms #signs
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... peripheries, Carpal ... Features #Signs #Symptoms ... #Diagnosis #PhysicalExam
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal ... - If GH excess ... malignancy Pathophysiology ... islet cell tumor, excess ... Endocrinology #Treatment #Pathophysiology
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
and menses • Pathophysiology ... the Na-K pump by excess ... thyroid hormone • Symptoms ... hours-days duration +/- symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
joint capsule exceeds ... boggy" joints, esp carpal ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Fecal bacteria access ... epithelium and causing symptoms ... Signs/Symptoms ... UrinaryTractInfection #LUTI #Pathophysiology ... #Signs #Symptoms