12 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... MunerMohamed1 #hyperkalemia ... #differential # ... diagnosis #pathophysiology ... #pharmacology #
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyperreflexia: • Hypocalcemia ... Testing #Causes #differential ... #diagnosis #table ... #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... with previously stable ... heart failure, neurologic ... disorders including hypokalemia ... Neurologic disorders
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... • LDH ↑ • Hyperkalemia ... per day until stable ... Rhabdomyolysis #Differential ... causes #treatment #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Dermatomyositis) AKI - Pathophysiology ... per day until stable ... Dialysis for severe hyperkalemia ... Rhabdomyolysis #Differential
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Inexpensive - Treats hypocalcemia ... edgarvlermamd - Nephrology ... Phosphate #Binders #Table ... #Comparison #Pharmacology ... #Nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) hypokalemic ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology ... #Hypokalemia