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diagnosis management differential signs erythematosus guillain hepatology lupus rheumatology sle systemic treatment alkaline alp causes clinical criteria cushings excess gammopathy
NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
Syndrome Features ... or hyporeflexia Features ... , Mild sensory symptoms ... Elevated CSF protein Features ... spectrum disorders Features
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... (+) Systemic Features ... (-) Systemic Features ... Ig deposition disease ... Differential #Diagnosis #hematology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Carpal Tunnel Syndrome ... Acne • Coarse features ... Cardiovascular disease ... diagnosis #signs #symptoms ... #endocrinology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... • The cardinal features ... than one after symptom ... #Syndrome #diagnosis ... #management #neurology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Diagnosis and Clinical Features ... , pathological fractures ... Diagnosis #signs #symptoms ... #endocrinology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• recurrent fractures ... Malnutrition • Wilson's disease ... mineralization Symptoms ... respiratory failure • Neurologic ... pain - Frequent fractures
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... resolution of HPS features ... resolution of symptoms ... hepatopulmonary #syndrome ... management #treatment #hepatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... Clinical Features ... Shrinking lung syndrome ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Dermatomyositis Clinical Features ... : • Triad of symptoms ... urine • Other symptoms ... of underlying disease ... causes #treatment #nephrology
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