12 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Incr Skeletal fractures ... , sleep apnea, cor
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... compression by fractured ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... differential #algorithm
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... Vertebral burst fracture
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Differential Diagnosis Algorithm ... vomiting, auditory symptoms ... Temporal Bone Fracture ... symptoms/signs, ... • Multiple sclerosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Progressive MS (Spinal cord ... #diagnosis #management ... #neurology #treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
multiple spinal cord ... and with limb features ... fasciculations Common Symptoms ... #Sclerosis #neurology ... #diagnosis #management
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Diagnosis: • Spinal cord ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Hyperreflexia develops later ... signs and/or symptoms ... : - Multiple sclerosis ... Myelitis #diagnosis #management ... #neurology #differential
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... failure Clinical Features ... • Natural history ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
4m • Atypical Features ... Isolated lower, bilateral ... ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... #Treatment #Neurology