12 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... CD8+ ratio are frequently ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology #
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Treatment: • Consider ... diagnosis #management #treatment ... #hematology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... heliotrope rash, Shaw sign ... , holster sign, ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most frequently ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
complications frequently ... systemic sx + signs ... systemic complaints- anemia ... Treatment of GCA ... them, but urgent rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(petechiae) • Frequent ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Syndromes #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Increasingly severe/frequent ... double contour sign ... • Acute gout treatment ... +Radiographic signs ... #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... chest (in a V-sign ... shoulders (in a shawl sign ... positive patients Treatment ... diagnosis #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... asymmetry may occur • Frequent ... Myositis #Myopathy #rheumatology