31 results
diagnosis hematology differential management lupus oncology signs algorithm abnormal disorders druginduced hemolysis hemolytic pathophysiology physicalexam sle symptoms treatment abnormalities acid
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... practices that could cause ... changes), high MCV anemia ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... for secondary causes ... eosinophilia (common ... causes are asthma
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... antibiotics are the most frequently ... Extravascular #Causes ... #anemia
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
e.g AEIOU ) or anuria ... if patient has common ... are caused by prerenal ... CONSIDER INTRINSIC CAUSES ... KidneyInjury #simplified #workup
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Excretion: Urine Common ... rapid injection; Nausea ... #Indications #Pharmacology ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Cytopenia - Less common ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
diarrhea, bloating [common ... rare with ~100 cases ... urticaria [quite common ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
- Cytopenia: Common ... • Immunologic Workup ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... cancers: Most common ... microorganisms or who have frequent ... autoimmune hemolytic anemia ... DDX - Other causes
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