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diagnosis treatment hemophagocytic hlh lymphohistiocytosis oncology differential hemeonc syndrome algorithm anemia anticoagulation blood bowel breakthrough chronic classification cll common cryofibrinogenemia
Causes of Breakthrough/Extension of Thrombosis and Management Algorithm #Anticoagulation #Breakthrough #Thrombosis #Algorithm #Extension #VTE #DVT #Hematology #Management
Causes of Breakthrough ... Thrombosis and Management ... Extension #VTE #DVT ... #Hematology #Management ... #Differential #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... idiopathic) - Autoimmune ... antibiotics are the most frequently ... Extravascular #Causes ... differential #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... old, ~10,000 new cases ... acute leukemia Management ... #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) - Summary ... ITP, AIHA, PRCA, autoimmune ... 6 months - Autoimmune ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
microorganisms or who have frequent ... : Pneumonia • Autoimmune ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Diagnosis and Management ... Summary Diagnosis ... Change in frequency ... Rifaximin- up to 3 courses ... Gastroenterology and Hepatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Summary ... associated with autoimmune ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
steroids • In mild cases ... with infection or autoimmune ... Options for severe cases ... HLH #Treatment #management ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Immunosuppression • Autoimmune ... Lymphoma (90-95% of cases ... classification #hematology ... #oncology #management
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