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diagnosis hematology causes pulmonary syndrome systemic treatment acquired ana anemia antibodies antinuclear classification common cvid diseases encephalopathy erythematosus extravascular hemolysis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune ... #patterns #rheumatology ... #diagnosis #differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Immune-mediated: - Autoimmune ... idiopathic) - Autoimmune ... antibiotics are the most frequently ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... in 24h Airway disease ... Kaposi's sarcoma • Rheumatologic ... / Autoimmune: ANCA-Assoc ... #Hemoptysis #Differential
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune ... disease • vWF ... #treatment #hematology ... #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
microorganisms or who have frequent ... : Pneumonia • Autoimmune ... thrombocytopenia and autoimmune ... and M panel Management ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... Erythematosus #Diagnosis #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... ANCA vasculitis ... life-threatening diseases ... Auto-antibodies: ANCA ... #diagnosis #management
Subglottic stenoses (SGS) during systemic diseases Subglottic stenosis (SGS) = congenital (children) or acquired (adult) characterized by
during systemic diseases ... • Immunology : ANCA ... Laryngotracheal cancer • Autoimmune ... #differential # ... diagnosis #causes #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... disease, Cancer ... circulation: MCA ACA ... Reversible course Differential ... Syndrome #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology ... #oncology #management
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