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treatment differential erythematosus hematology lupus sle systemic chronic classification cll common cryoglobulinemia cryoglobulins cvid hemeonc hemophagocytic hlh hypogammaglobulinemia immunodeficiency immunology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... Summary • Epidemiology ... Evolution: Chronic disease ... #Management #Summary ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary ... Antinuclear (ANA ... Erythematosus #SLE #Summary ... #diagnosis #rheumatology ... #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
microorganisms or who have frequent ... : Pneumonia • Autoimmune ... thrombocytopenia and autoimmune ... and M panel Management ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) - Summary ... minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... #hemeonc #diagnosis ... #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... Autoimmune ANCA ... life-threatening diseases ... Auto-antibodies: ANCA ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
solid cancers • Autoimmune ... diseases: SLE++ ... Adult-onset Still disease ... #management #treatment ... #summary #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... diseases: - 10% ... Labs/Diagnosis: ... DDX: • ANCA (Antineutrophil ... classification #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis - Summary ... Sclerosis (MS) is an autoimmune-mediated ... neurodegenerative disease ... Ataxia • GU: Frequent ... #management #neurology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... RP-ILD), dermato-rheumatologic ... asymmetry may occur • Frequent ... Myositis #Myopathy #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
mesothelioma, etc - Autoimmune ... Sjögren’s syndrome, ANCA-associated ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
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