11 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency (CVID ... CVID: Immunodeficiency ... microorganisms or who have frequent ... specifically immune thrombocytopenia ... hypogammaglobulinemia #immunology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... IgA, IgG, IgM (CVID ... patients with thrombocytopenia ... if the cause of thrombocytopenia ... Causes #Workup #hematology
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
immune thrombotic thrombocytopenia ... vaccination with certain COVID ... platelet count (thrombocytopenia ... immune #thrombotic #thrombocytopenia ... #COVID #pathophysiology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
our practice to frequently ... Diagnosis #Management #Hematology ... Heparin #Induced #Thrombocytopenia
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... ♀, ↑Age, ESRD Pathophysiology ... consumption → thrombocytopenia ... emcrit.org/ibcc/thrombocytopenia ... Management #Treatment #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Liver, IBD • COVID ... Heparin-induced thrombocytopenia ... fulminans - COVID ... Venous #Arterial #pathophysiology ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... protein C and S Pathophysiology ... DITMA) - MAHA + Thrombocytopenia ... coagulopathy - Thrombocytopenia ... treatment #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... antibiotics are the most frequently ... differential #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... (petechiae) • Frequent ... IDUS) • Immune Thrombocytopenia ... Syndromes #diagnosis #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
standing for: - Thrombocytopenia ... severe fever with thrombocytopenia ... cell lymphoma Pathophysiology ... diagnosis #management #rheumatology ... #Thrombocytopenia