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hematology differential algorithm management aplastic causes workup oncology syndromes apl arteritis auer auerrods blood bloodsmear bonemarrow cancer clinical common cvid
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Syndromes with Pancytopenia ... Fanconi Anemia ... lauraebrown #Pancytopenia ... #diagnosis #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... - Differential Diagnosis ... Toxins • Aplastic Anemia ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... deficiency • Fanconi’s anemia ... #Differential #Diagnosis ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Acquired Aplastic Anemia ... #Differential #Diagnosis ... #Algorithm #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... Diagnosis: • Pancytopenia ... #diagnosis #management ... #treatment #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Acquired Aplastic Anemia ... #Differential #Diagnosis ... #Algorithm #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... bone marrow + pancytopenia ... • Peripheral Pancytopenia ... #oncology #hematology ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Microangiopathic hemolytic anemia ... antibiotics are the most frequently ... #differential #diagnosis ... #hematology #anemia
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
presented with pancytopenia ... promyelocytes, anemia ... large in size with frequent ... She was diagnosed
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 Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #Differential #Diagnosis ... Causes #Workup #hematology
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