14 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms ... abn lipid • GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... Acne • Coarse features ... diagnosis #signs #symptoms ... #endocrinology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
growth hormone (GH ... Acromegaly #Signs #Symptoms ... #Diagnosis #Endocrinology
Features of hyperthyroidism and hypothyroidism

#hyperthyroidism #hypothyroidism #features #signs #symptoms #endocrinology
Features of hyperthyroidism ... hypothyroidism #features ... #signs #symptoms ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
coarsening facial features ... • GH stimulates ... level (↑Sens) - GH ... (Lanreotide) ± GH ... Diagnosis #Management #Endocrinology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Syndrome - Signs and Symptoms ... Increased risk of fractures ... Syndrome #Signs #Symptoms ... #diagnosis #endocrinology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Rickets Dysmorphic Features ... Cushing's Disease • GH ... Diagnosis #Algorithm #endocrinology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... #Hypothyroid #Features ... #Signs #Symptoms ... #PhysicalExam #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
facial or acral features ... Growth Hormone (GH ... Algorithm #diagnosis #endocrinology