53 results
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
The triquetrum ... fractured carpal bone ... "pooping duck sign ... common carpal bone ... "pooping duck sign
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
in subchondral bone ... architecture -> Palpable bony ... contact between bony ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... , Fragile bones/ ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Chvostek's Sign - Physical Exam - Hypocalcemia

Chvostek's sign is described as the twitching of facial muscles
Chvostek's Sign ... Chvostek's sign ... absent in about one ... #Chvosteks #Signs ... #Hypocalcemia #Video
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
tenderness • Positive one-legged ... XR — scotty dog sign ... MSK #diagnosis #pathophysiology ... #signs #symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... Disease #Diagnosis #Signs
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... destroying thin bony ... inner cortical bone ... #Mastoiditis #pathophysiology ... #signs #symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Sporadic mutation -> One ... gene mutated in one ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs