24 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Pathophsiology ... Lysosomal storage disorder ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... variability in disease ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... pylori test (GI symptoms ... ), (neurologic/psychiatric ... candidate) - Bone ... #Differential #
Short Bowel Syndrome - Acute and Chronic Adverse Signs and Symptoms of Ileal Resection
 • Dehydration
Short Bowel Syndrome ... and Symptoms of ... Nephropathy • Bone ... #Signs #Symptoms ... Ileal #Resection #pathophysiology
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... rubbing • Atopic diseases ... / Symptoms / Complications ... #Keratoconus #pathophysiology
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Vascular disorders ... the headache (in one ... Syndrome usually ... varying neurologic signs ... Vertigo #Causes #differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... and signs below ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Myeloproliferative Disease ... Neutropenia • Platelet Disorders ... blood count with differential
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
evaluation should be done ... hypertension and signs ... renal bruit or signs ... Renal parenchymal disease ... Neurologic disorders
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... lymphoproliferative disorders ... Warm AIHA • Bone