91 results
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... the first-line treatments ... which reduces bone ... #Pharmacology #Pathophysiology
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease ... by an ↑ rate of bone ... • The disease ... medperspective #Pagets #Disease ... #management #treatment
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology
Alzheimer's Disease - Summary
 • Epidemiology
 • Pathophysiology
 • Risk Factors
 • Presentation
 • Diagnosis
 •
Alzheimer's Disease ... Epidemiology • Pathophysiology ... Diagnosis • Treatment ... #Alzheimers #Disease
Gastritis and Peptic Ulcer Disease - Etiology, Diagnostics, Treatment and Complications

#Diagnosis #Pathophysiology #Management #Gastritis #PepticUlcerDisease #PUD
and Peptic Ulcer Disease ... , Diagnostics, Treatment ... #Diagnosis #Pathophysiology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... Unknown cause Treatment
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... decreased reflexes Pathophysiology ... of bacilli to bone ... CXR should be done ... CMC_IM #Potts #Disease
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... and lower jaw Treatment ... osteoarticular and skin disease