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diagnosis management hematology chronic cll hemeonc hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis classification coccidiodomycosis encephalopathy fungal hivaids hodgkins infectiousdiseases lymphoma mds
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... #summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Complications: 1) Infection ... chemotherapy for low-risk disease ... - Progressive bore ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
IDSA Recommendations ... with positive serology ... BII)* Treating Bone ... Extrathoracic Disseminated Disease ... #Prevention #Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... extrapulmonary disease ... or meningitic disease ... by culture or serology ... Aspergillosis Pathophysiology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... cells can indicate disease ... microglobulin Treatment ... Warm AIHA • Bone ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Myeloproliferative Disease ... • Parvovirus infection ... Syndromes #diagnosis #hematology ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Diagnosis: • Infection ... epilepticus Treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... anymore • Routine bone ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
fast bacterial infection ... cell lymphoma Pathophysiology ... interfollicular zone ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Triggers: ▪ Infections ... ▪ Autoimmune diseases ... Pathophysiology ... Hemophagocytosis in bone ... underlying trigger: Infections
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