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differential algorithm management signs symptoms hematology msk nephrology treatment oncology orthopedics physicalexam workup clinical complications disorders endocrinology rheumatology secondary hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... Rule out other causes ... as the collar bone
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
excessive bone ... turnover -> Incr bone ... Incr (abnormal) bone ... PagetsDisease #pathophysiology ... #diagnosis #signs
Hypophosphatemia - Differential Diagnosis Algorithm • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use • Redistribution/
- Differential Diagnosis ... malabsorption), Hungry bone ... syndrome • Renal ... #Algorithm #causes ... #nephrology #phosphate
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm True Vertigo - Illusion of Rotary Movement Peripheral Vestibular
- Differential Diagnosis ... Media • Temporal Bone ... Dizziness #Vertigo #Neurology ... #Differential #Diagnosis ... #Algorithm #Causes
Fat Embolism Syndrome Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Trauma to the long bone ... accounts for —9096 of cases ... Pathophysiology ... Fat #Embolism #Syndrome
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
D) Increased bone ... Paget's disease of bone ... Multiple myeloma (bone ... • Milk-alkali syndrome ... endocrinology #diagnosis
Causes of Hypomagnesemia • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Postparathyroidectomy (hungry bone ... metastasis (hungry bone ... #differential #diagnosis ... #nephrology #magnesium
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... Postparathyroidectomy (hungry bone ... metastasis (hungry bone ... Hypomagnesemia #Causes ... #diagnosis #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... Aplastic Anemia • Bone ... the blood and bone ... blood smear • Bone
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