16 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Screen for HLH ... HLH syndrome 5. ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Screen for HLH ... HLH syndrome 5 ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... juvenile idiopathic arthritis ... fever syndromes Clinical ... Fever is the main clinical ... juvenile idiopathic arthritis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... Assessment • Clinical ... /ml, ↑ LDH • Bone ... treatment #summary #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... • Inflammatory arthritis ... the subchondral bone ... Joint #Pain #MSK #rheumatology ... #approach #workup
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... : Overwhelming clinical ... / Diagnosis: HLH ... Hemophagocytosis in bone ... management #treatment #hematology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... node biopsy • Clinical ... values supporting hematologic ... Bone marrow biopsy ... UnknownOrigin #workup
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... nonerosive inflammatory arthritis ... Diagnosis: • A clinical ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... association • M > F Clinical ... Behcet syndrome (Clinical ... SLE, Reactive arthritis ... signs #symptoms #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... back pain) • HLA-B27 ... ANA and RF (if clinical ... #laboratory #workup ... diagnosis #testing #Rheumatology