28 results
diagnosis signs symptoms clinical management syndrome complications differential msk dermatology diabetic disease hepatology infection neurology neuropathic orthopedics osteomyelitis summary ucsdh
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Syphilitic gummas in Tertiary syphilis Tertiary syphilitic gummas may mimic basal cell carcinoma. The gummatous tumors are
treated, in most cases ... vessels, liver, bones ... syphilis #clinical #photo
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Bisphosphonate suppresses bone ... damage weakens the bone ... #differential #causes ... #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Complications #pathophysiology
Fat Embolism Syndrome Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Trauma to the long bone ... accounts for —9096 of cases ... Pathophysiology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... months temperate zones ... 10% Crab, few cases ... consumption First case ... legs #clinical #photo
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... excessive bone ... Skull expansion causes ... causes middle ear ... PagetsDisease #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Drugs, Unknown cause ... 100 mg/m2) : in case
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... of the temporal bone ... hearing loss, nausea ... inner cortical bone ... #Mastoiditis #pathophysiology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... use of N2O can cause ... anemia includes bone ... #Pathophysiology
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