16 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... gastric bypass), LFT ... (liver disease) ... candidate) - Bone
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Others #LFTs ... #Differential # ... Diagnosis #Algorithm #Causes
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
- Differential ... be used by the bone ... is made in the liver ... Hematologic Malignancy ... saturation to differentiate
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... • Liver (80%) ... Intestine - Other causes ... ALP #Elevation #Differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... Green boxes indicate ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... hemolysis) • ALP: Bone ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Drug induced - Bone ... deficiency • Liver ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... infiltration) Differential ... Intrahepatic Cholestasis Management ... #Pregnancy #hepatology ... obgyn #diagnosis #management