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diagnosis treatment differential syndrome algorithm oncology gastroenterology liver anemia rheumatology dermatology hemophagocytic hepatic hlh lymphohistiocytosis workup alkaline alp aplastic blood
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... Manifestations and Management ... #Diagnosis #Management ... #Hematology #SickleCell
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long bones ... BrighamChiefs #Bone ... differential #diagnosis #causes ... #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... • Bone marrow ... acute leukemia Management ... #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... candidate) - Bone ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Causes of Leukocytosis and Leukopenia - Differential Diagnosis • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... Drugs, Autoimmune, Bone ... Differential #Diagnosis #causes ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... • Secondary Causes ... Drug induced - Bone ... Differential #Diagnosis #hematology ... #rheumatology #
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... Renal disease - Bone ... Diagnosis #Algorithm #hepatology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone ... significance (MGUS) A bone ... algorithm #diagnosis #management ... #hematology #multiplemyeloma
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