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differential aplastic causes diffuse lymphadenopathy management mds myelodysplastic bandemia cbc chronic cll focal hematololgy localized lymphocytic myelodysplasia neutrophil syndrome syndromes
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
- Differential Diagnosis ... Algorithm • Reactive ... • Neoplastic (Leukemia ... Lymphadenopathy #LAD ... #Hematology #Oncology
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... Expectation • Rx Algorithm ... #diagnosis #oncology ... #hematololgy
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... Lymphadenopathy #LAD ... #Algorithm #Causes ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... • Bone marrow ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... activity • ↓ LAP ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... • Neutropenia, anemia ... Warm AIHA • Bone ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... virus (EBV) • Leukemia ... • Suggested by bone ... #oncology #hematology ... #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... Tissue damage • Leukemia ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... compounds, alcohol, lead ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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