117 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... BrighamChiefs #Bone ... differential #diagnosis #causes ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • softening of bones ... Hypotonia - Pain (muscle ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could cause ... candidate) - Bone ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
arrhythmias, seizures; muscle ... causing MN death -> Muscle ... invade URT & via hematologic ... CNS and hematologic ... > Inflammation causes
TISSUE APPEARANCES ON 
MUSCULOSKELETAL ULTRASOUND 

Bone:
 
Bone is represented as a very bright structure and appears
MUSCULOSKELETAL ULTRASOUND ... Bone: Bone ... can pass through bone ... Muscle: Muscle ... Nerve: Ultrasound
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... • Secondary Causes ... Drug induced - Bone ... Differential #Diagnosis #hematology ... #rheumatology #
Osteomalacia & Osteoporosis in People with HIV
Osteomalacia:
 - Decreased bone matrix mineralization. In people with HIV
- Decreased bone ... (from multiple causes ... ) - Bone pain/ ... ribs), Proximal muscle ... of underlying cause
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... Drugs, Autoimmune, Bone ... Differential #Diagnosis #causes ... #hematology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
cardiac & skeletal muscle ... cardiac & skeletal muscle ... AlkP) - Liver, bone ... brain, NOT in bone ... Interpretation #diagnosis #hepatology