194 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... hyperplasia of bone ... #Workup #Hematology ... #Diagnosis *
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... BrighamChiefs #Bone ... #differential #diagnosis ... #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... candidate) - Bone ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
the articular bone ... Peri-articular osteopenia (bones ... #RA #HandXray #Diagnosis ... #Radiology #Clinical ... #Pathophysiology
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... - Differential Diagnosis ... Drugs, Autoimmune, Bone ... #Differential #Diagnosis ... #causes #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... • Secondary Causes ... Drug induced - Bone ... #Differential #Diagnosis ... #hematology #rheumatology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
- Differential Diagnosis ... be used by the bone ... Hematologic Malignancy ... #Differential #Diagnosis ... #Causes
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... Causes: 1) Exfoliative ... Skin-homing T-cells #Diagnosis ... #Dermatology #Rash
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule ... out other causes ... #Dermatology