Triquetrum bones hematology hepatology table algorithm liver management diagnosis acute injury dili

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17 results

Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
• Intrinsic - predictable, dose dependent

Diagnosis and Management ... Injury (DILI) ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology

for acute liver ... injury #Liver ... #Injury #Acute ... #Evaluation #Algorithm ... #Diagnosis #Hepatology

Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... #Acute #Liver # ... Injury #Causes #

Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,

Injury (DILI) - ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology

Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500):
• NAFLD
• Cirrhosis
•

- Differential Diagnosis ... Hepatopathy • Acute ... (>1000): • DILI ... injury) • Ischemic ... #hepatology #transaminitis

Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)

Acute-on-Chronic ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis

Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury:
• Hepatic vein:

Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... hemolysis) • ALP: Bone ... #algorithm #hepatology

Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for

abnormality vs bone ... Bili - Direct ... Hepatocellular injury ... Transaminitis #diagnosis ... #hepatology

Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
• R >

hemolysis) • ALP: Bone ... Unconjugated Bili ... > 90% of Total Bili ... #chemistry #diagnosis ... #differential #Hepatology

Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
• Infectious: Hepatitis C, A,

Liver Injury - Differential ... Diagnosis Hepatocellular ... #Diagnosis #Causes ... #Acute #algorithm ... #hepatology

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