15 results
diagnosis oncology treatment rheumatology dermatology hemophagocytic hlh syndrome blood mds myelodysplastic product reactions activation anemia aplastic atopic atopy classification dermatitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Drugs, Unknown cause ... #diagnosis #management
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... • Secondary Causes ... Drug induced - Bone ... Differential #Diagnosis #hematology ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Hemophagocytosis in bone ... Hemophagocytic #Lymphohistiocytosis ... #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
haemophagocytic lymphohistiocytosis ... hemophagocytic lymphohistiocytosis ... is found in the bone ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... • Bone marrow ... acute leukemia Management ... #treatment #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
, joint, and skin ... • Pustular skin ... Rule out other causes ... #diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... Options for severe cases ... Hemophagocytic #Lymphohistiocytosis ... HLH #Treatment #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Headaches • Pale skin ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... cells - Blood and Bone ... -> AML: Blast crises ... CLL -> Invade Skin ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... that are caused ... Out Secondary Causes ... Syndromes #diagnosis #hematology
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