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Treatment Approach to Hodgkin's Lymphoma

By Matthew Ho, MD PhD @MatthewHoMD
With Credit: Dr Sunita Nasta and Dr
Treatment Approach to Hodgkin's ... By Matthew Ho, MD ... guidelines #Hodgkins ... #Lymphoma #oncology ... #Hematology #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... anymore • Routine bone ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome (MD ... • Bone marrow ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Transfusions: Cellular blood ... Patients with Hodgkin ... Daniela Hermelin, MD ... Irradiation #RBC #Blood ... #Indications #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... Warm AIHA • Bone ... diagnosis #workup #oncology ... #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... Summary Framework Hematologic ... MGUS #Monoclonal #Gammopathy ... #Significance #hematology ... #diagnosis #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... Hypocellular/Hypoplastic MDS ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... just beneath the skin ... platelets) • MDS ... Syndromes #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Infection exposure (l MD ... plateletcount), peripheral blood ... candidate) - Bone ... or if a primary hematologic ... Causes #Workup #hematology