34 results
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... damage weakens the bone ... Femur #Fractures #msk ... #differential #causes ... #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease - MSK ... fragmentation and mild bone ... • MRI is more sensitive ... patella #clinical #mri ... Radiology #diagnosis #msk
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology
Imaging Findings:
 • Arrows identifying the characteristic edema-like signal
FOPE lesion) - MSK ... physeal fusion and bone ... repeated follow-up MRI ... • Bone contusion ... lesion #clinical #mri
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... suspected, immediate MRI ... CaudaEquina #Syndrome #MSK ... #pathophysiology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... • Bone and joint ... Rule out other causes ... - MRI: inflammation ... and lower jaw Treatment
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... formation MSK ... Skull expansion causes ... causes middle ear ... PagetsDisease #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Treatment: • ... diagnosis #management #treatment
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... cord compression (MRI ... change on spinal MRI ... out • Brain MRI ... Transverse Myelitis Treatment
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
Disease (HADD) - MSK ... Case description ... • MRI shows globular ... • Treatment for ... Disease #clinical #mri