31 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... • XR, MRI to ... #differential #diagnosis ... #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Bone marrow ... Myelodysplastic #Syndrome ... #hematology #oncology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... - MRI: inflammation ... diagnosis #management ... #Dermatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... folate def - Bone ... antiphospholipid syndrome ... #Framework #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Drug induced - Bone ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
more: • Clonal bone ... focal lesions on MRI ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Budd Chiari Syndrome (BCS)

Diagnosis
Clinical Manifestations
Causes
Management

By Dr. Hima Veeramachaneni @hima_vee via @EmoryGastroHep

#BCS #BuddChiari #Budd #Chiari #Syndrome #Hepatology
Budd Chiari Syndrome ... (BCS) Diagnosis ... Manifestations Causes ... #Hepatology #Gastroenterology ... #diagnosis #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Constitutional Syndromes ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... - Aneurysmal bone ... Knee #Effusions #causes ... #msk #physicalexam