20 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... • XR, MRI to ... #differential #diagnosis
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
- Differential Diagnosis ... Tumors #Tumours #MSK ... #Differential #Diagnosis ... #Algorithm #Orthopedics ... #Causes #Oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
more: • Clonal bone ... focal lesions on MRI ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential Diagnosis ... Tumours - See Bone ... Fractures #Pathologic #MSK ... #Algorithm #Orthopedics ... #Causes
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Peripheral Vascular Disease ... Marfan's Syndrome ... Vascular #JointPain #MSK ... #Algorithm #Orthopedics ... #Causes
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... • MRI is more sensitive ... patella #clinical #mri ... #msk
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
- Differential Diagnosis ... Sicca) Syndrome ... Inflammatory #JointPain #MSK ... #Algorithm #Orthopedics ... #Causes
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
- Differential Diagnosis ... Osgood-Schlatter Disease ... Intraarticular #MSK ... #Algorithm #Orthopedics ... #Causes
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... and less common diseases ... Non-inflammatory causes ... neuropathy (LHON) plus MRI ... consistent with MS
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... - MRI: inflammation ... osteoarticular and skin disease ... #Rheumatology #diagnosis