38 results
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... consistent with bursitis ... tibial tuberosity Differential ... marrow edema and bony
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... • XR, MRI to ... BrighamChiefs #Bone
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Intra-Articular - Bone ... • Aseptic Bursitis ... Osgood-Schlatter Disease ... Ganglion Cyst - Bone ... Intraarticular #MSK
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
• Sickle Cell Anemia ... Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... #Orthopedics #Causes
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
cornea), poor bone ... • Vitamin D - Bone ... • Thiamine - Nausea ... : • Calcium - Bone ... nutrition #table #differential
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Tumours - See Bone ... • Bone Marrow ... Fractures #Pathologic #MSK ... #Differential # ... #Orthopedics #Causes
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... excessive bone ... turnover -> Incr bone ... formation MSK ... PagetsDisease #pathophysiology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... g/dl LLN B - Bony ... more: • Clonal bone ... focal lesions on MRI ... Causes of false-
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Bisphosphonate suppresses bone ... damage weakens the bone ... Femur #Fractures #msk ... orthopedics #diagnosis #differential ... #causes #pathophysiology