29 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... signs #symptoms #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
damage weakens the bone ... Femur #Fractures #msk ... #orthopedics #diagnosis ... #differential #causes ... #pathophysiology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease - MSK ... fragmentation and mild bone ... • MRI is more sensitive ... patella #clinical #mri ... #msk
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Difficulty walking Diagnosis ... Phosphatase: • Other causes
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology
Imaging Findings:
 • Arrows identifying the characteristic edema-like signal
FOPE lesion) - MSK ... physeal fusion and bone ... repeated follow-up MRI ... • Bone contusion ... #msk
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... suspected, immediate MRI ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... formation MSK ... causes middle ear ... PagetsDisease #pathophysiology ... #diagnosis #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Tuberculosis - Diagnosis ... extrapulmonary cases ... decreased reflexes Pathophysiology ... of bacilli to bone ... : - MRI is modality
Freiberg Infraction - MSK Radiology
Imaging Findings:
 • Sclerosis of the 2nd MT head with flattening of
Freiberg Infraction - MSK ... Case description ... plate, subchondral bone ... foot #clinical #mri ... #msk
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... Transverse #Myelitis #diagnosis ... #management #neurology