15 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... Differential Diagnosis Algorithm ... Most common symptoms ... symptoms - Pain ... Differential #Diagnosis #Algorithm
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low Alkaline ... collection with EDTA Pathophysiology ... mineralization Symptoms ... of Low Alkaline
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Differential Diagnosis Algorithm ... Tumours - See Bone ... Pelvis - Positive Alkaline ... Gastrointestinal Disease • Bone ... Marrow Disorder
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Lysosomal storage disorder ... Osteonecrosis, bone ... Diagnosis #Signs #Symptoms
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... suspicious clinical symptoms ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... LFTs #Abnormal #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... Classification #pathophysiology ... #differential #algorithm
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Mucous membranes • Bone ... musculoskeletal symptoms ... Psychiatric symptoms ... weeks #Scurvy #Pathophysiology ... #AscorbicAcid #Pathophysiology
Functional GI Disorders in IBD - IBD Algorithm

Background:
 • 25-40% of IBD in remission have IBS
in IBD - IBD Algorithm ... remission have IBS symptoms ... correlation of lBS-type symptoms ... narcotic use FGID Pathphysiology ... IBDAlgorithm #IBD #Algorithm
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... suspected HH based on symptoms ... and hematologic disorders ... ALT, alanine aminotransferase ... hemochromatosis #algorithm
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
cause excessive bone ... turnover -> Incr bone ... Nerve Palsies • Disordered ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms