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diagnosis anemia differential management leukemia mds myelodysplastic algorithm approach calculation causes cll hodgkins index infections infectiousdiseases lymphocytic lymphoma mycobacteria myelodysplasia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... Deficiency • Aplastic ... • Anemia of Chronic ... Non-lmmune #Anemia #Classification ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... • Suggested by bone ... hypoplasia/fatty bone ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... • Bone marrow ... Management #treatment #hematology ... #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
• Anemia of chronic ... deficiencies: Chronic ... Hypogonadism • Bone ... marrow failure: Aplastic ... Production #Index #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Pure red cell aplasia ... Warm AIHA • Bone ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... involvement CML (Chronic ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... Causes • Anemia • Aplastic ... Marrow Failure • Chronic ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... anymore • Routine bone ... lymphoma #diagnosis #classification ... #hematology #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Immunocompromised status • Chronic ... encounters due to NTM: Chronic ... Growers (Runyon Classification ... Hematologic malignancy ... ) - Bone Marrow
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