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management differential rheumatology hepatology oncology syndrome treatment algorithm arthritis causes complications hemophagocytic hlh lymphohistiocytosis pagetsdisease ra sclerosis summary abnormal agammaglobulinemia
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm True Vertigo - Illusion of Rotary Movement Peripheral Vestibular
- Differential Diagnosis ... vomiting, auditory symptoms ... • Meniere's Disease ... Media • Temporal Bone ... symptoms/signs,
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... candidate) - Bone
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
• CNS symptoms ... thin smear • Signs ... values supporting hematologic ... Bone marrow biopsy ... #diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... of bacilli to bone
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... skin thickening Signs ... and Symptoms: ... #diagnosis #signs ... #workup
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... but elevated as disease ... #workup #hepatology
Short Bowel Syndrome - Acute and Chronic Adverse Signs and Symptoms of Ileal Resection • Dehydration
Chronic Adverse Signs ... and Symptoms of ... Nephropathy • Bone ... #Resection #pathophysiology ... #diagnosis
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