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diagnosis signs complications management syndrome alkaline alp anorexianervosa ascorbicacid barre bulimianervosa causes differential disorders encephalopathy endocrinology gbs guillain hematology hepatology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... /joint pain Psychiatric ... Symptoms: Disorientation ... Secondary #Tertiary #pathophysiology
Paget’s Disease: Pathogenesis and Clinical Findings • Incr serum CTx - marker of bone resorption •
CTx - marker of bone ... resorption • Lytic bone ... formation #PagetsDisease ... #pathophysiology ... diagnosis #signs #symptoms
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
cause excessive bone ... turnover -> Incr bone ... hearing loss #PagetsDisease ... #pathophysiology ... diagnosis #signs #symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• softening of bones ... of feet, thigh bones ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Mucous membranes • Bone ... • Persons with psychiatric ... musculoskeletal symptoms ... Psychiatric symptoms ... #AscorbicAcid #Pathophysiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... (CVID, WAS), (neurologic ... /psychiatric changes ... candidate) - Bone
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Transplantation including bone ... Etiology: • Pathophysiology ... Neurological symptoms ... diagnosis #management #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
surgery, trauma, and bone-marrow ... than one after symptom ... the underlying pathophysiology ... diagnosis #management #neurology
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
/ Hypovolemia NEUROLOGIC ... Osteoporosis - Low bone ... Complications #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
hormone levels cause bones ... Complications #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry
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