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diagnosis liver transaminitis algorithm chemistry dili drug function gastroenterology idiosyncratic induced interpretation patterns rvalue tests
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... ) - Differential ... Hepatopathy • Acute ... Drug-induced liver injury ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Mixed - Check Acute ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
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