9 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... of Pregnancy (AFLP ... defects. 1) HELLP (Hemolysis ... #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... defects. 1) HELLP (Hemolysis ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Schistocytes, thrombocytopenia ... inclusions - If infection ... #Anemia #Differential ... Algorithm #workup #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
HELLP Syndrome (Hemolysis ... , Thrombocytopenia ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... specifically immune thrombocytopenia ... and autoimmune hemolytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Infectious ... Bilirubin: RBC (hemolysis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... DIC/TTP/HUS - Hemolytic ... SLE) - Viral infections ... APLS • Acute Infectious
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... petechiae) • Frequent infections ... Macrocytic anemia DDX ... • Parvovirus infection ... blood count with differential