22 results
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Clinical Manifestations ... 20%) congenital infection ... -7 Fever, exanthema-subitum-like ... Microbiology #Diagnosis #Comparison ... #Table
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... ), EBV infection ... - Pel-Ebstein fever ... Alcohol-induced pain ... : Pain in involved
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... pain/Night sweats ... Weight loss - DDX ... Brucellosis - Viruses: HIV
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... since cART) Aspergillus ... Microsporidium #Lung #Infections ... #differential #
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
invasive fungal infection ... cut-offs defined in clinical ... surfaces - Infections ... BAL GM does not differentiate ... Galactomannan #diagnosis #comparison
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
positives: IVIG, IV ... surfaces, Albumin, Infections ... Spec 81% for dx ... >90% (In most clinical ... in BAL does not differentiate
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
known as rat bite fever ... or Haverhill fever ... (HSV + Mycoplasma ... PrathitKulkarni #Erythemas #comparison ... #table #differential
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... weight • Chest pain ... , CCP, ANCA • HIV ... aeruginosa • Aspergillus ... Bronchiectasis #pulmonary #differential
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... Infections 2. ... symptoms - Headache, fever ... Nausea, abdominal pain ... #table
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... Mycoplasma, EBV, HIV ... younger pts) Differential ... Symptoms: High fevers ... chills, flank pain