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diagnosis management causes oncology vasculitis algorithm allergy anemia aplastic classification common cvid dermatology disorders framework hemeonc heparin hit hypogammaglobulinemia immunodeficiency
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... etc) - Viral: HIV ... infiltration: malignancy, infection ... Diagnosis #Framework #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Quinidine • HIT ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... procedures - Infection ... or if a primary hematologic ... Platelet #Disorders #Differential ... Causes #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... SLE) - Viral infections ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... specifically immune thrombocytopenia ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... skin necrosis (at injection ... consumption → thrombocytopenia ... re-challenge >100d after Dx ... Management #Treatment #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... /fevers • Thrombocytopenia ... Idiopathic • Infections ... and thymoma DDX ... Anemia #oncology #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... Framework The DDx ... NSAIDs/Aspirin, IV ... • Parasitic infections ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... to exclude are infections ... CTD) • ANCA (Dx ... Cryoglobulins • HIV ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... Macrocytic anemia DDX ... • Parvovirus infection ... blood count with differential ... Syndromes #diagnosis #hematology
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