17 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... or functional neutropenia ... Phosphorus CLL ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Differential Diagnosis Algorithm ... Myelofibrosis Stem cell ... #Pancytopenia #Neutropenia ... #Causes #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
infections from neutropenia ... Consider stem cell ... antibiotics if neutropenic ... fever) Complications ... management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... between classical CLL ... Cytopenias: • Neutropenia ... leukemia #CLL ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... Thrombocytopenia, Neutropenia ... d-dimer, ↓ NK cell ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... ) B symptoms → fevers ... PRCA, autoimmune neutropenia ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell ... bartonella (oroya fever ... Differential #Diagnosis #Algorithm ... #workup #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Encapsulated Bacteria Cell ... CNS Infection Neutropenia ... Infection #Fever ... #Causes #Hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... a decrease in all ... peripheral blood cell ... primarily seen as neutropenia ... Red cell distribution
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most frequently ... following: • Fever ... Low or absent NK cell ... management #treatment #hematology