18 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... abnormalities • Muscular ... Disease #diagnosis #management ... #treatment #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Clinical DX: - ... immunologic assay - MuSK ... Gravis #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... intrapulmonary vascular ... shunt (Type 2) Clinical ... Intra-pulmonary vascular ... #treatment #hepatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... (Clinical Dx). ... Behcet disease) Differential ... Arthritis, AS Treatment ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... anterior chest wall, parts ... Diagnosis: • A clinical ... and lower jaw Treatment ... diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
cortical lesions • Vascular ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
Intermittent Bilateral Exophthalmos (Alternating Exophthalmos and Enophthalmos) on Physical Exam

Observing this patient in silence for a
Treatments are aimed ... The syndrome of ... Differentials for ... Commonly, vascular ... Alternating #Bilateral #clinical
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management ... #neurology #treatment
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... Symmetric macular ... Albuminuria, nephrotic syndrome ... ulcerated • MSK ... stages #diagnosis #management