46 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Perilunate Dislocation
On lateral wrist XR, the capitate ("apple") should sit in the lunate ("tea cup") which
tea cup") which should ... trapezium, capitate, triquetrum ... Radiology #XRay #Diagnosis ... #Orthopedics #Sports ... #MSK
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... #Algorithm #Causes ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... possible, patients should ... athletic regimens should ... #Management #treatment ... #hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
validated for VTE treatment ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology ... #Diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... #differential #diagnosis ... #causes #hematology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
50 years in men Diagnosis ... More likely to cause ... myasthenia usually • Starts ... glucocorticoids - can cause ... within 3 years of diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... aspirin • Aspirin should ... PolycythemiaVera #PV #Diagnosis ... #hematology