21 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
: Proximal tubule ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... in the distal tubule ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Defects in Kidney Tubule ... ascending limb Gitelman ... distal convoluted tubule ... Liddle syndrome ... Defects #Kidney #Nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... blood flow • Tubular ... damage • Tubular ... #Mechanisms #pathophysiology ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... distal convoluted tubule ... , Renal tubular ... #nephrology #management ... #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
hypokalemia • Renal tubular ... , Gitelman's syndrome ... acid, Liddle's syndrome ... • Cushing's syndrome ... algorithm #causes #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... high in kidney tubular ... in the proximal tubule ... urine #Algorithm #nephrology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... caseyalbin #PhysicalExam ... #neurology #comatose
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
and Myotomes Reflexes ... • Cauda Equina Syndrome ... neck such as fibular ... Myotomes #diagnosis #neurology ... sensory #motor #leg #physicalexam