29 results
Non-infective endocarditis Characteristics and Pathophysiology

By Dr. Sara Dong @swinndong via #IDFellowCase

#ID  #Infectious Diseases  #Infections
#Differential
Non-infective endocarditis ... Characteristics and Pathophysiology ... #Infections #Differential ... #BCNIE #CNIE #Endocarditis ... #Cardiac #Pathophysiology
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
for Infective Endocarditis ... #Infective #Endocarditis ... Pathogens #Diagnosis #Differential ... #InfectiousDiseases
Non-Infective Endocarditis (NBTE / Marantic Endocarditis)
Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
Non-Infective Endocarditis ... NBTE / Marantic Endocarditis ... embolize • Cannot differentiate ... absent How can we differentiate ... Marantic #diagnosis #pathophysiology
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
negative infective endocarditis ... BCNIE #Causes #differential ... culture #negative #Endocarditis ... #InfectiousDiseases
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Pupillary Defects - Differential ... • Optic Nerve Tumor ... dissociation) • Pharmacologic ... • Botulism Pharmacologic ... Pupils #Defects #Differential
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Cryoglobulinemia, Endocarditis ... Glomerulonephritis #Vasculitis #differential
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Infectious • Endocarditis ... Myasthenia Gravis Pharmacologic ... Chronic #Fatigue #Differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
#hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Endocarditis Summary ... Marantic (NTBE) Differential ... Metastatic disease and tumor ... embolism Endocarditis ... #Endocarditis
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... Acute bacterial endocarditis ... • Infective endocarditis ... Hyper-IgD syndrome • Tumor ... Fever #Patterns #Differential