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diagnosis differential management myasthenia causes cardiology clinical emergencies endocarditis eyelid generalized hemeonc infections mycobacteria myelitis neuromuscular nontuberculous ntm ocular oncologic
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Myelitis, Trauma, Tumor ... Motor Nerves: ALS ... Syndrome, Myasthenia Gravis ... differential #diagnosis #neurology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... : UMN (stroke, tumor ... Polyneuropathy, ALS ... #Generalized #Weakness ... Diagnosis #causes #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
with: - Thymic tumors ... variable degree of weakness ... Limb- proximal weakness ... Generalized fatigue - ALS ... diagnosis #management #neurology
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia Gravis ... non-localized EOM weakness ... Myasthenia gravis ... have a thymic tumor ... ophthalmology #neurology
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 Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
disorder (Cardiac, pulmonary ... system: Brain tumor ... Postsynaptic: Myasthenia Gravis ... aminotransferases • Serology ... Differential #Diagnosis #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... or respiratory weakness ... for thymoma, a tumor ... #Myasthenia #Gravis ... diagnosis #management #neurology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... including therapy with tumor ... • Malaise, • Weakness ... k_vaishnani and Ravi ... differential #diagnosis #infectiousdiseases
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
rapid onset of weakness ... monophasic Pathophysiology ... Weakness: - Weakness ... Enhancement - TM and tumor ... diagnosis #management #neurology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... low Ca - q8 h TLS ... Lower-extremity weakness ... renal failure, pulmonary
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Sanguinis, Mitis, Oralis ... Cerebral > Splenic, Pulmonary ... Metastatic disease and tumor ... Diagnosis #cardiology #infectiousdiseases
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