18 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... meningococcal, H1N1) Clinical ... Clinical Features ... Syndrome #diagnosis #management ... #treatment #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Myelitis, Trauma, Tumor ... Poliomyelitis, Guillain-Barre ... heavy metals), Critical ... Weakness #Causes #differential ... #diagnosis #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... #Diagnosis #hematology ... #oncology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... the underlying pathophysiology ... specific therapy, the clinician ... Syndrome #diagnosis #management ... #neurology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... infiltration) Differential ... Maternal Support - Critical ... Liver #Pregnancy #hepatology ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... extranodal) - Tumor ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
patients with minimal tumor ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... CMV) • Epstein-Barr ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... include a: • Neurologic ... tympanic membrane • Neurologic ... Labyrinthitis ○ Epstein-Barr ... #Diagnosis #otology