29 results
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... • Down, Turner ... , Marfan syndromes ... #Keratoconus #pathophysiology ... #ophthalmology
Differential Diagnosis for ST Segment Elevations
 - ACUTE STEMI 
 - PULMONARY EMBOLISM 
 - LBBB
Differential Diagnosis ... ) - BRUGADA SIGN ... (SYNDROME) - ... SPIKED HELMET SIGN ... #Diagnosis #Cardiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
, Orbital apex syndrome ... URGENT: Brainstem tumor ... Miller-Fisher syndrome ... mass #Diplopia #differential ... #diagnosis #ophthalmology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... Leukostasis: • Pathophysiology ... hyperviscosity syndrome ... WBC >100k, + lab signs ... • Pathophysiology
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Pupillary Defects - Differential ... Midbrain (Parinaud's Syndrome ... ): • Tumor • ... Pupils #Defects #Differential ... Algorithm #Causes #Ophthalmology
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
Holmes-Adie Syndrome ... Young females Differential ... trauma/orbital tumor ... PhysicalExam #neurology #ophthalmology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Behcet disease) Differential ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... • Tumor-induced ... • Nephrotic syndrome ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... Acute Coronary Syndrome ... #Diagnosis #Pathophysiology ... #causes #cardiology