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diagnosis management tls causes differential high hyperkalemia nephrology emergencies hematology hemeonc leukemia oncologic tumorlysis uricacid
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ≥ 8 mg/dL • Potassium ... ICU transfer • Tumor ... MatthewHoMD #TLS #Tumor ... #Lysis #Syndrome
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... Lysis Syndrome ... 8.0 mg/dL • Potassium ... #TumorLysis #Syndrome ... diagnosis #management #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... Treatments: • IV ... wandering_er #Tumor ... #Lysis #Syndrome ... #TLS #oncology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
potassium • Beta ... release due to cell lysis ... Transfusion reaction - Tumor ... lysis syndrome ... diagnosis #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
potassium • Beta ... release due to cell lysis ... Transfusion reaction - Tumor ... lysis syndrome ... diagnosis #causes #potassium
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... Intracellular Urate, Potassium ... Leukemia #Hematology #Oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... fever: - Fever + ANC ... afebrile 24-48 h and ANC ... antibiotics TLS (tumor-lysis ... #Emergencies #Oncology
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