10 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... high WBC count cause ... /- rasburicase Tumor ... #Tumor #Lysis # ... Syndrome #TLS #diagnosis
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... #Tumor #Lysis # ... Syndrome #diagnosis ... #management #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome (TLS ... Laboratory TLS ... #diagnosis #management ... #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Leukostasis: • ... EMERGENCIES: Tumor ... Constipation • Nausea ... #differential #diagnosis
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
Excessive IV Mg infusion ... Mechanisms - Tumor ... #Differential #Diagnosis ... Magnesium #Table #Causes ... #Management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... Treat underlying cause ... anticoagulation Leukostasis ... #HemeOnc #Diagnosis
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... : laparoscopic tumor ... reserved for large or invasive ... tumors. ... (chemotherapy, tumor
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... ↑ Can develop leukostasis ... Fibrinolysis & DIC • Tumor ... Leukemia #Hematology #Oncology ... #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Classification: • The tumor ... predominant HL - The tumor ... lymph node biopsy (diagnostic ... classification #hematology #oncology ... #management
Hamartomatous Polyposis Syndromes - Peutz-Jeghers Syndrome (PJS), Juvenile Polyposis Syndrome (JPS), Cowden Syndrome (CS), Cronkhite-Canada (CC),
Pancreas + Sex Cord Tumor ... fronds I "Pseudo-invasion ... BMPR1A gene → Tumor ... Polyposis #Syndromes #diagnosis ... #management #gastroenterology